Pvalb^{tm1.1(Ncre)Mdes}

Mice were generated by inserting a 2A sequence, the N-terminal fragment of cre recombinase (aa 19-59) fused to the intein-N peptide fragment (123 N terminal amino acids of the DnaE split intein sequence) and Frt-flanked PGK-neomycin resistance cassette immediately in front of the stop codon of parvalbumin coding sequence by homologous recombination. The Frt-flanked PGK-neomycin resistance cassette was removed by crossing with transgenic mice expressing Flpo. (J:253250)