CRISPR/Cas9通过基因编辑技术,替换了大部分exon 2(包括起始密码子),用上了mTurquoise2(远蓝绿色荧光蛋白)的编码序列,还插入了-loxP引导的诺卡因抗性(neo)基因座。表达报告基因受内源性基因启动子调控。(来源:J:252680)
Basic Information
(C57BL/6J x CBA/J)F1 x C57BL/6JIcoCrlLumc
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count