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中文
在LoxP位点通过同源重组，在exon 2上游插入，exon 14下游，实现了对这些位置的插入。通过ES细胞中Cre介导的重组，导致了exons 2至14的缺失。这一缺失导致了蛋白质的N-deacetylase和N-sulfotransferase功能丧失。对大脑RNA的RT-PCR分析确认了纯合突变小鼠中mRNA转录本的缺失。（来源：J:252046）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
