Log In|Sign Up
中文
在前导序列1上游插入了loxP位点，随后在内含子2中插入了FRT序列和puromycin抗性基因座，再配以第二个loxP位点。通过后续的Flp介导重组，去除了puro cassette。通过Cre介导的重组，去除了exons 1和2，形成了无表达的突变体。qRT-PCR和免疫印迹实验确认了这个等位基因的表达缺失。（来源：J:243638）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
