Tg(TTR)#Jbux

This transgene contains the human transthyretin gene containing the endogenous general promoter, liver specific enhancer, and tissue specific regulator. This line contains approximately 90 copies of the human insert per diploid genome. Northern blot confirmed expression of mRNA in the liver, eye, and brain and small amounts in tongue, kidney, heart, skeletal muscle, and stomach. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:68458)