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中文
通过同源重组，5号和6号外显子被一个含 floxed Pgk-neo 标记的 cassette 替换。随后，Cre介导的重组去除了neo cassette。RT-PCR结果显示，短的、占主导地位的1500bp转录本缺失，但检测到了一个1215bp的第二条转录本，它跳过了5和6号外显子，包含一个新插入的exon 7。然而， Western blot 检测并未发现任何蛋白质产物。(来源：J:244973)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
