这个靶向构建包含了slice接受器(loxP位点)、两个polyaden化序列、FRT引导的诺卡因抗性元件、STOP序列、第二个loxP位点、人源的Simian二价链球菌毒素受体(结合肝素的表皮生长因子样生长因子)、内含子序列、tdTomato报告基因和另一个polyaden化序列。通过Flp介导的重组,抗性元件被移除,但STOP序列保持了可翻转状态。(来源:J:263766)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
Targeted
插入
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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