将含有CD3E基因的人工cosmid cEpsilon1注入BDF2受精卵中。建立了五条独立的克隆:三条拷贝数低的和两条拷贝数高的。这个等位基因表示的是低拷贝,有5个转录本插入。北标显示,人类基因以正确的T细胞特异性方式表达。(来源:J:172562)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F2
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插入
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1
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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