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中文
靶向载体包含一个由FRT引导的诺卡因(neo)抗性元件，它被插入在第3外显子下游。第4外显子被修改，以在第92和93位氨基酸位置（S92A-L93A）插入 Alanine。这些突变位于铰链区域，与TH17细胞的分化相关。通过Flp介导的重组，FRT引导的neo元件被移除。（来源：J:248565）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
