Tg(KRT10-Nfe2l2)#Swnr

The transgene comprises the following elements: the bovine keratin 10 promoter, a rabbit beta-globin intron, a cDNA for the constitutively active isoform of the mouse Nfe2l2 gene which lacks sequence for the N-terminal Neh2 domain, and human growth hormone gene poly(A) features. Three mouse lines, with expression levels similar to or lower than the endogenous gene, were established after pronuclear injection of FVB/N fertilized oocytes. The pound # sign is used in the allele symbol because no line was specified. (J:160519)