Log In|Sign Up
中文
这段DNA序列包含了β-半乳糖苷酶(lacZ)的报告基因和由人UBC和细菌EM7启动子驱动的诺卡因抗性基因，周围带有loxP位点。它替换了目标基因的32kb区域，包括4到21号外显子。通过qRT-PCR，证实了这种敲除等位基因的转录显著减少。无论是qRT-PCR还是酶学检测，都未检测到lacZ活性。(来源：J:243171)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
