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中文
这个突变是在Jackson实验室通过向细胞注射Cas9 RNA和四种指导序列（TTACACCTCCCCATTAGAGC、GCCTGGGCTTCTGTGCAACT、AGCTTTTTAGTCATAGCCAA和ATTATCTGAGATTTAATCAA）产生的，导致了19号染色体负链从59,042,109bp开始，到59,041,661bp之后的449bp缺失。这个变异删除了ENSMUSE00000288532（第4外显子）以及354bp的上下游内含子序列，包括剪接点的接受者和供体，预测会导致第57位氨基酸序列改变以及随后的两个早期终止密码子。信息来源：(J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
