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中文
在第15和16个内含子中插入了LoxP位点，并将第16外显子的GAA编码的谷氨酸替换为CAA（p.E446Q）。这种突变预计会影响蛋白质的功能。随后通过Flp介导的重组移除了内含子15中的kanamycin-neomycin抗性基因座。Cre介导的重组则去除了修饰的第16外显子。（来源：J:243488）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
