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中文
在R1 ES细胞中，通过同源重组技术在Tac2基因的终止密码子和polyA位点间插入了一个Frt-neo-Frt-IRES-cre cassette。经过定向编辑的ES细胞被注入C57BL/6的囊胚中。产生的嵌合动物与C57BL/6J小鼠杂交，然后与表达Flp重组酶的品系杂交，以去除Frt标记的neo cassette。来源：(J:234023)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
