这个转基因是通过一个人类细菌人工染色体(BAC)RP11-150L1设计的,包含了完整的人类TLR4基因。建立了5271号突变体,它携带着两个拷贝的转基因。BAC包含TLR4基因周围至少50KB的人类基因组序列。(来源:J:194866)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C3H or C57BL/6
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插入
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1
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3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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