TALEN技术针对起始翻译位点产生了11个碱基的缺失,包括ATG, Western blot结果显示杂合体中蛋白质表达减少了超过50% (来源:J:235912)
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TALEN technology targeting the translation start site generated an 11 bp deletion including the ATG. Western blot analysis confirmed a greater than 50% reduction of protein expression in heterozygotes. (J:235912)