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中文
靶向载体被设计成在基因的第10外显子下游插入一个由loxP序列标记的诺卡因(neo)抗性元件。在第11外显子引入了一个T到G的转换，对应于人类氨基酸468的位置，产生了S467A的变异。通过Cre介导的重组，上游的含floxed neo的元件被去除了。(来源：J:251115)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
