在chr7大约1.2MB的区域,从chrna7到fan1,包括这两个基因(chrna7和fan1)的编码区域,以及mtmr10, trpm1, klf13和otud7a,通过flp介导的重组,chrna7tm1mima和fan1tm1mima产生了这个缺失。这个区域内的基因表达在杂合子小鼠的脑组织中有所降低。(来源:J:227984)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6NTac
Targeted
插入,基因间区删除,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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