Tg(HBx-HCV)C5Tto

The hepatitis B virus X gene (Px) promoter drives the expression of the hepatitis C virus-core cDNA (HCV-1b strain). Northern blot and Western blot analysis confirmed mRNA and protein expression in livers and various tissues including thymus, spleen, brain, heart, lung, kidney intestine, and testis. Two lines, C5 and C8 were established Line C5 is the high expressing line. (J:243110)