The hepatitis B virus X gene (Px) promoter drives the expression of the hepatitis C virus-core cDNA (HCV-1b strain). Northern blot and Western blot analysis confirmed mRNA and protein expression in livers and various tissues including thymus, spleen, brain, heart, lung, kidney intestine, and testis. Two lines, C5 and C8 were established Line C5 is the high expressing line. (J:243110)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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