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中文
在第13个内含子插入了LoxP位点，接着是带有IRES-EGFP-Luciferase元件的 cassette，FRT引导的neo cassette以及在第17个外显子的终止密码子后插入了LoxP位点。通过Flp介导的重组，neo cassette被去除了。在杂合子和纯合子的MEFs中，mRNA表达分别降至野生型水平的大约70%和30%。（来源：J:227638）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
