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中文
设计了一个p2lox导向的质粒，它旨在通过替换现有Cre重组酶ORF，利用loxP和lox2272位点，将人类DUX4开放阅读框(ORF)和3'端非翻译区(UTR)后面跟着poly A尾巴插入到tetO启动子前。下游位置放置了一个无功能的诺瓦克抗性基因(neo)。这个构建通过诱导 cassette exchange (ICE)重组，插入到Hprt基因上游的 cassette exchange locus。来源：(J:243630)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
