将含有En转录接点、lox71位点、lacZ基因、neo cassette、loxP位点和lox2272位点的pUC17基因捕获载体插入了内皮4号染色体。插入导致内源序列在前320bp后截断,催化区域丢失。定量实时PCR确认了E11期胚胎中转录几乎不存在(来源:J:242754)。

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NCrlj x CBA/JNCrlj)F1
Gene trapped
基因捕获载体的插入
--
1
1
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部