Log In|Sign Up
中文
心脏特异性的小鼠α肌动蛋白重链启动子驱动了人类心脏肌动蛋白（actin）的表达，其中第361位氨基酸由谷氨酸（Gly，E361G）替换为甘氨酸。这是一种显性负性突变。我们建立了两条品系：361.20和361.13。这些小鼠在心脏中表达这种突变，大约占总肌动蛋白的50%。（来源：J:242344）
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
