在编码24个保守且功能必需的胱氨酸残基中的20个的3号和4号外显子周围插入了LoxP位点。这些携带这种等位基因的鼠与CMV-Cre小鼠杂交,以删除LoxP引导的区域。(来源:J:242196)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129X1/SvJ
Targeted
基因内删除
--
1
7
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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