这个靶向载体包含一个diphtheria毒素A阴性选择座(DTA)后面跟着由loxP位点分隔的3到6号外显子,再后面是一个由frt位点包裹的诺如霉素阳性选择座(NeoR)。Cre介导的重组会去除3到6号外显子以及NeoR座。来源:(J:241919)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
插入,基因内删除
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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