CRISPR/Cas9技术在单一编码外显子引入了135bp的缺失。 Western blot分析在E16.5和P0时确认了肢体和舌部没有蛋白表达(来源:241565)
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CRISPR/Cas9 technology introduced a 135 bp deletion in the single coding exon. Western blot analysis confirmed the absence of protein expression in limb and tongue at E16.5 and P0. (J:241565)