L1L2_gt0 cassette被插入到染色体2的115,972,39位置,位于关键外显子(基于GRCm38构建)。这个 cassette包含FRT引导的lacZ/诺卡因序列,后面跟着插入到内含子3的loxP位点,再额外插入一个loxP位点到内含子4。通过Flp介导的重组,去除了FRT标记的LacZneo cassette,使得exon 4成为可翻转的。(来源:J:239305)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Targeted
插入
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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