Fgfr2^tm2.1Sor

The targeting vector is designed to replace the stop codon in exon 19 of the Fgfr2 gene with a cassette containing a human HIST1H2BB gene [histone 1 H2bb] sequence, a viral 2A oligopeptide (T2A) that mediates ribosomal skipping, a red fluorescent protein (mCherry) sequence, and a new stop codon. An FRT-flanked neomycin resistance (neo) cassette was inserted in the intron upstream of exon 19. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:241560)