使用了含有近淋巴细胞蛋白酪氨酸激酶(Lck)启动子驱动Cre重组酶的转基因构建,在NOT/Sytwu小鼠中建立了一条转基因品系。总共产生了至少两条,标记为7和14。Cre重组酶的表达具有特异性的T细胞模式。(引用信息:J:194560, J:202955)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
NOD/ShiLtJSyt
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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