在 intron 2 中插入了 loxP 立场,随后将一个 FRT-loxP-诺卡因-FRT-loxP 的 cassette 导入了 intron 3。通过 Flp 介导的重组,FRT 包围的 neo cassette 被移除,留下 exon 3 为可调节的。(来源:J:241281)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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