使用含有FMS样转录因子Foxp3驱动Red Fluorescent Protein(RFP)和cre/ERT2融合基因的构建,成功在C57BL/6小鼠中建立了转基因品系。RFP在CD4+CD25+细胞中表达。cre重组酶在颅骨、肺、卵巢、棕色脂肪和阴囊淋巴结中表达。(来源:J:202955)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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