使用含有FMS样转录因子Foxp3驱动Red Fluorescent Protein(RFP)和cre/ERT2融合基因的构建,成功在C57BL/6小鼠中建立了转基因品系。RFP在CD4+CD25+细胞中表达。cre重组酶在颅骨、肺、卵巢、棕色脂肪和阴囊淋巴结中表达。(来源:J:202955)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count