使用含Ctsk驱动RFP和cre/ERT2融合基因的构建,通过转染技术在C57BL/6小鼠中建立了一个转基因品系。在tamoxifen诱导后,cre重组酶在骨、脑、眼、肾、肾上腺、肺、脾、胸腺、胃、胰腺、骨骼肌、小肠、阑尾、睾丸和附睾、白色和棕色脂肪以及皮肤中激活。(来源:J:202955)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
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