插入PGK_EM7_PuDtk_bGHpA cassette导致了8号染色体(Genome Build 38)上一个从128,359,209到128,359,325的缺失。这个缺失去除了该微小RNA的DNA序列。该 cassette 包含一个loxP位点、一个F3位点、一个PGK-puromycin-delta-tk cassette、另一个loxP位点和一个FRT位点。(来源:J:174268)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N-Atm1Brd
Targeted
插入,基因内删除
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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