包含Otp基因座的BAC RP24-337G4通过重组修复,将Otp编码序列替换为Cre重组酶。这个BAC还整合了Tbca基因的2-4号外显子,没有插入其他基因。经过修改的BAC被注入到受精卵中。(来源:J:240674)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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