Log In|Sign Up
中文
一段编码鼠TNNC1(心肌/慢肌troponin C)的cDNA，携带有L48Q(CTG到CAG)突变和FLAG标签，被置于小鼠Myh6(心肌肌动蛋白重链6，α型)启动子以及tetO响应元件的调控下。翻译以人类生长激素的poly(A)信号终止。当转录活跃时，该转基因能导致大约40%的突变型心肌troponin C整合进心肌肌原纤维中。(来源：J:234490)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
