在exon 14的上游插入了一个loxP位点,然后在exon 15之后插入了一个由两个loxP位点 flank的neo cassette。通过诱导的Cre重组酶,去除了含loxP标记的neo cassette,留下exons 14-15两侧的loxP位点。(来源:J:166948)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Targeted
插入
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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