在X染色体的mouse Brs3基因在终止密码子后插入了IRES-Myc标签-核定位信号(NLS)-cre-GFP-frt-neomycin-frt。通过同源重组,这个neomycin cassette通过与广泛表达Flp重组酶的动物杂交被剔除。(来源:J:101977, J:308449)
Basic Information
(129S6/SvEvTac x C57BL/6NCrl)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count