Log In|Sign Up
中文
CRISPR/Cas9技术产生了一个在第740和741位由ACA变为ATG的突变，导致第247位的丝氨酸变为甲硫氨酸。这个突变预测会导致泛素连接酶活性丧失。 Western blot结果显示，目标蛋白水平显著降低，可能是因为突变蛋白的半衰期缩短了。(来源：J:260672)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
