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中文
在exon 1的上游插入了CAG启动子和loxP序列标记的 puromycin抗性基因和ECFP报告基因的双元件，替换掉了原有的天然启动子。随后通过cre介导的重组，移除了选择/报告元件，使得该基因受CAG启动子的恒定激活控制。这种等位基因的表达量大约是野生型的十倍。转录本的半衰期与野生型相同。(来源：J:239949)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
