通过EUCOMM载体(PG00126_Z_3_B08)使用flp介导的重组,从最初通过敲除产生的人β-actin启动子和SV40polyA控制下的FRT-flanked lacZ序列、loxP位点及诺卡因 cassette中创建了一个条件性可诱导的准备好(floxed)等位基因。这个等位基因保留了exon 5两侧的loxP标记。(引用信息:J:227476, J:235694)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NTac
Targeted
插入
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1
6
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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