使用了Bacterial artificial chromosome(BAC)库(CHORI)来获取一个包含整个小鼠paired box 7 Pax7基因的BAC(编号#RP23-218H13)。这个BAC经过改造,将Pax7基因的首段编码外显子替换为来自大肠杆菌的增强绿色荧光蛋白(ZsGreen)。在E9.5时,小鼠的这些部位——脊索、面中线结构和神经管——开始发出绿色荧光,而到E10.5时,荧光强度有所增强。(来源:J:239659)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
CD-1
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11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
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