A 1500 bp deletion was introduced by CRISPR/cas9 endonuclease mediated genome editing 4 kb upstream of the Nr4a1 transcription start site in the Nr4a1 super enhancer (se) sub-domain E2. The deletion spans 101,262,166-101,263,744 (GRCm38/mm10). Nr4a1 gene expression is not altered. (J:239509)