一个新霉素抗性基因座替换了exon 1。 Western blot分析证实了在小鼠胚胎成纤维细胞和肝脏中蛋白表达的缺失。(来源:J:238622)
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A neomycin resistance cassette replaced exon 1. Western blot analysis confirmed the absence of protein expression in mouse embryonic fibroblasts and liver. (J:238622)