CRISPR/Cas技术针对Kit基因上游240kb区域和Nmu基因下游81kb处,设计了一个1.07Mb的删除区域,其中包括多个基因。左边的CRISPR靶点位于染色体5:75,408,459-75,408,481,右边的靶点位于5:76,444,361-76,444,383(基于GRCm38构建)。(来源:J:233978)
Basic Information
Intergenic deletion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count