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中文
Exon 3通过CRISPR/Cas9系统进行了靶向，sgRNA的序列是5'-CACCTAGCCTCGCACGAActt-3'(识别序列大写)，实验中产生了5个碱基的缺失(CTCGC)，在识别序列的中间。由此产生的框架移位导致了一个早期终止密码子，导致基因功能丧失。 Western blot结果显示，纯合子小鼠中这个等位基因翻译出的肽类没有被检测到。(来源：J:239003)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
