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中文
这个Chmp7-8200J-F4216项目的等位基因是在Jackson实验室通过向细胞注射Cas9 RNA和四种指导序列(GGAAATGTAAAAATAACCCA, GCTGATTACTTCCGGACAGT, GTTAATATAATGCCTCTGAG, TGCGACAGACAGCCTGTCCT)产生的，导致了从14号染色体负链69,730,348bp的CAGGCTGTCTGTCGCATTAC起始，到69,729,964bp的TAGGGTTATATATTCCTTGG终止的385bp缺失。这个变异删除了213bp的上游和下游内含子序列，包括剪接点的接受者和捐赠者，预测会导致100号残基后的氨基酸序列改变以及随后的25个氨基酸的早期截断。(来源：J:188991)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
