通过Flp介导的重组,移除了FRT-删除的lacZ序列、loxP座、诺卡因 cassette,这些都受到人类β-actin启动子和SV40 polyA的控制,从而创建了一个条件性可诱导的准备好(floxed)等位基因。剩下的部分是5-7号外显子被loxP座标记。(来源:J:232606)
Basic Information
(C57BL/6 x 129P2/OlaHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count