通过Flp介导的重组,移除了FRT-删除的lacZ序列、loxP座、诺卡因 cassette,这些都受到人类β-actin启动子和SV40 polyA的控制,从而创建了一个条件性可诱导的准备好(floxed)等位基因。剩下的部分是5-7号外显子被loxP座标记。(来源:J:232606)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129P2/OlaHsd)F1
Targeted
插入
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1
2
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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