将无终止密码的人类α-synuclein基因cDNA连接到EGFP的5'端,通过PDGF-beta启动子进行调控。获得了五条转基因品系,其中表达最高的是75和78号。这些转基因品系中人类α-synuclein mRNA的表达水平相当于人脑水平的三倍。(来源:J:238692)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
--
插入
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
微信
信息比对
科研助手
使用教程
回到顶部