这个靶向载体包含一个由loxP切割位点介导的PGKneo假基因插入,位于Biotin-3xFLAG(BioFL)序列上游(编码生物素识别序列和3个FLAG抗原决定簇),该序列连接在基因的C端。通过Cre酶介导的重组,去除了上游的floxed neo假基因元件。(来源:J:101977)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S4/SvJae)F1
Targeted
插入
--
1
22
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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