这个靶向载体包含一个由loxP切割位点介导的PGKneo假基因插入,位于Biotin-3xFLAG(BioFL)序列上游(编码生物素识别序列和3个FLAG抗原决定簇),该序列连接在基因的C端。通过Cre酶介导的重组,去除了上游的floxed neo假基因元件。(来源:J:101977)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count