整个小鼠Mpz基因(包括6kb的启动子序列,所有外显子和内含子,以及自然的poly(A)位点),作为转录本,被用来构建转基因。在编码区域的末尾插入了myc标签。总共产生了12条转基因小鼠,保留了线140.12进行后续研究。(来源:J:171510)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
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插入
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1
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2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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